Scientific publications

Clinical trial10 patients · first-in-human pilot trial

First-in-human trial of atrial fibrillation ablation using real-time tissue optical assessment to predict pulsed field lesion durability

After pulsed field ablation the bipolar electrograms disappear, so it is hard to judge right away how durable the resulting lesion is. In patients with paroxysmal atrial fibrillation, the authors tested for the first time in humans a new system that shows structural changes in the tissue optically during ablation, and checked the result with repeat mapping after 3 months. Lesions at sites where the optical signal dropped by more than a certain threshold proved durable; no serious adverse events related to the system were recorded.

Authors

Raphael P. Martins, Giorgi Papiashvili, Askar Sabirov, Sherzod Sabirov, David Herranz, Christophe Bailleul, Atul Verma

Sherzod Sabirov's position

author 4 of 7

Affiliation

Ezgu Niyat Medical Center, Tashkent, Uzbekistan

Published in

Europace. 2025;27(2):euaf009. doi:10.1093/europace/euaf009

Funding and conflicts of interest: The study was sponsored and funded by MedLumics. The authors’ statements on conflicts of interest are given in the article itself.

Original article13 patients · original research article

The simultaneous endocardial and epicardial mapping of the left atrium in patients with long-persistent atrial fibrillation

The cause of fibrillation and the mechanisms that sustain it are not yet fully understood. In this work, in 13 patients with long-standing persistent fibrillation, the left atrium was mapped simultaneously from its inner and outer surfaces with 64-pole electrodes during the “Maze IIIB” operation; frequency and amplitude maps were built and compared with fibrosis on magnetic resonance imaging. The authors showed that in such patients frequency and amplitude activity in the left atrium is low, and developed a method of simultaneous mapping.

Authors

L.A. Bockeria, R.Z. Shalov, A.G. Filatov, V.A. Goryachev, Sh.N. Sabirov

Sherzod Sabirov's position

author 5 of 5 · Junior research fellow

Affiliation

Bakulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russia

Published in

Annaly aritmologii. 2019;16(4):184–193. doi:10.15275/annaritmol.2019.4.1

Experiment20 pigs · experimental study

The results of thoracoscopic mapping and radiofrequency ablation of ventricular tachycardia experimentally

The source of ventricular tachycardia is sometimes located deep in the myocardium or close to the epicardium; in such cases endocardial ablation is ineffective. In an experiment on 20 pigs, a method of thoracoscopic (through small openings in the chest) epicardial mapping of both ventricles and radiofrequency ablation on the beating heart was tested and compared with left-sided thoracotomy. In both groups access to all walls was achieved and circulation parameters remained stable; the authors rated the method as safe and accurate.

Authors

L.A. Bockeria, O.L. Bockeria, M.B. Biniashvili, Sh.N. Sabirov, T.V. Nazimov

Sherzod Sabirov's position

author 4 of 5 · Junior research fellow, cardiovascular surgeon

Affiliation

Bakulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russia

Published in

Annaly aritmologii. 2019;16(3):120–128. doi:10.15275/annaritmol.2019.3.1

Case report1 patient · case report

The case of simultaneous endocardial and epicardial mapping of the left atrium when performing "Maze IIIB" procedure

A 64-year-old patient was found to have atrial fibrillation and mitral and tricuspid valve insufficiency. During open-heart surgery the left atrium was mapped simultaneously from its inner and outer surfaces, and then the “Maze IIIB” operation was performed. Computer analysis of the recorded electrograms showed quickly and accurately where the high-frequency activity was located during fibrillation. In the authors’ view, this may help to understand the mechanism of fibrillation and to make the operation more effective.

Authors

A.G. Filatov, R.Z. Shalov, Sh.N. Sabirov

Sherzod Sabirov's position

author 3 of 3 · Junior research fellow

Affiliation

Bakulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russia

Published in

Annaly aritmologii. 2019;16(2):96–102. doi:10.15275/annaritmol.2019.2.6

Case report1 patient · case report

Radiofrequency ablation of atrial tachycardia in a patient with a left superior vena cava

In a 32-year-old patient, atrial tachycardia (up to 160 beats per minute) returned 15 days after ablation of an accessory pathway. Drainage of the left superior vena cava into the coronary sinus made it difficult to pass the electrodes and to hold the ablation electrode firmly in place; this was solved with a long introducer. Radiofrequency energy at a point above the coronary sinus ostium stopped the tachycardia, and it did not start again; no complications were observed.

Authors

A.G. Filatov, T.D. Alatsiev, E.Kh. Shafiev, I.A. Temirbulatov, Sh.N. Sabirov

Sherzod Sabirov's position

author 5 of 5 · Junior research fellow, cardiovascular surgeon

Affiliation

Bakulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russia

Published in

Annaly aritmologii. 2018;15(4):230–234. doi:10.15275/annaritmol.2018.4.6

Case report1 patient · case report

Effective surgical treatment of multiple accessory pathways together with Ebstein’s anomaly and Wolff–Parkinson–White syndrome

A 37-year-old patient had been known since childhood to have Ebstein’s anomaly and Wolff–Parkinson–White syndrome; pre-excitation persisted even after ablation in 2000, and in 2018 the tachycardia returned. The electrophysiology study found several accessory pathways, and catheter radiofrequency ablation was performed. Complete atrioventricular block was then found (the authors consider that it may be congenital: it had not been noticed before because of the multiple pathways), and a permanent pacemaker was implanted; the patient was discharged in satisfactory condition on day 6. The authors: such a method may be safe and effective, but as a first stage it suits only patients whose tricuspid valve changes are small and whose circulation is not impaired.

Authors

A.G. Filatov, Ya.B. Yakh’yaev, T.D. Alatsiev, Sh.N. Sabirov, S.R. Vlasyants

Sherzod Sabirov's position

author 4 of 5 · Junior research fellow, cardiovascular surgeon

Affiliation

Bakulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russia

Published in

Annaly aritmologii. 2018;15(4):225–229. doi:10.15275/annaritmol.2018.4.5

ReviewReview article · two authors

Diagnosis and treatment of epicardial ventricular tachycardias

The source of ventricular tachycardia is sometimes located in the deep or outer (epicardial) layer of the heart wall. The review examines how common epicardial tachycardia is, the criteria for recognizing it in advance from cardiogram signs, and the results of combining inner and outer mapping and ablation. The authors’ conclusion: an epicardial source is one of the most common reasons why endocardial ablation is ineffective; combining both approaches increases success, and in experienced centers epicardial ablation is safe and effective.

Authors

L.A. Bockeria, Sh.N. Sabirov

Sherzod Sabirov's position

author 2 of 2 · Postgraduate student

Affiliation

Bakulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russia

Published in

Annaly aritmologii. 2015;12(4):234–244. doi:10.15275/annaritmol.2015.4.5